Skip to main content

Advertisement

Log in

Is anterior resection of the rectosigmoid safe after preoperative radiation?

  • Published:
Diseases of the Colon & Rectum

Abstract

Forty patients with carcinoma of the rectum or rectosigmoid underwent preoperative irradiation, followed by anterior resection with anastomosis. The radiation dose was 4500 rads administered in 25 fractions over a period of five weeks. One to three weeks after the radiation was completed, anterior resection of the rectosigmoid with anastomosis was done. Of the 40 patients, 23 had hand-sewn anastomoses and 17 had EEA stapled anastomoses. Fourteen of the 40 had diverting loop colostomies, all colostomies were subsequently closed, and there were no clinical postoperative anastomotic leaks. Anterior resection and anastomosis are considered to be technically safe with the surgical and radiation techniques used.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Nichols RL, Broido P, Condon RE, Gorbach SL, Nyhus LM. Effect of preoperative Neomycin-Erythromycin intestinal preparation on the incidence of infectious complications following colon surgery. Ann Surg 1973;178:453–62.

    Article  PubMed  CAS  Google Scholar 

  2. Smith LE. Anastomosis with EEA stapler after anterior colonic resection. Dis Colon Rectum 1981;24:236–46.

    PubMed  CAS  Google Scholar 

  3. Goligher J. Surgery of the anus rectum and colon. 5th ed. London: Bailliere Tindal, 1984:540–1.

    Google Scholar 

  4. Cass AW, Million RR, Pfaff WW. Patterns of recurrence following surgery alone for adenocarcinoma of the colon and rectum. Cancer 1976;37:2861–5.

    Article  PubMed  CAS  Google Scholar 

  5. Gilbertsen VA. Adenocarcinoma of the rectum: incidence and locations of recurrent tumor following present-day operations performed for cure. Ann Surg 1960;151:340–8.

    Article  Google Scholar 

  6. Gunderson LL, Sosin H. Areas of failure found at reoperation (second or symptomatic look) following “curative surgery” for adenocarcinoma of the rectum: clinicopathologic correlation and implications for adjuvant therapy. Cancer 1974;34:1278–92.

    Article  PubMed  CAS  Google Scholar 

  7. Kligerman MM. Preoperative radiation therapy in rectal cancer. Cancer 1975;36:691.

    Article  PubMed  CAS  Google Scholar 

  8. Stevens KR Jr, Allen CV, Fletcher WS. Preoperative radiotherapy for adenocarcinoma of the rectosigmoid. Cancer 1976;37:2866–74.

    Article  PubMed  Google Scholar 

  9. Cummings BJ, Rider WD, Harwood AR, Keane TJ, Thomas GM. Radical external beam radiation therapy for adenocarcinoma of the rectum. Dis Colon Rectum 1983;26:30–6.

    PubMed  CAS  Google Scholar 

  10. Friedmann P, Park WC, Afonya II, et al. Adjuvant radiation therapy in colorectal carcinoma. Am J Surg 1978;135:512–8.

    Article  PubMed  CAS  Google Scholar 

  11. Glimelius B, Graffman S, Pahlman L, Rimsten A, Wilander E. Preoperative irradiation with high-dose fractionation in adenocarcinoma of the rectum and rectosigmoid. Acta Radiol Oncol 1982;21:373–9.

    PubMed  CAS  Google Scholar 

  12. Kligerman MM, Urdaneta N, Knowlton A, Vidone R, Hartman PV, Vera R. Preoperative irradiation of rectosigmoid carcinoma including its regional lymph nodes. AJR 1972;114:498–503.

    CAS  Google Scholar 

  13. Pilepich MV, Munzenrider JE, Tak WK, Miller HH. Preoperative irradiation of primarily unresectable colorectal carcinoma. Cancer 1978;42:1077–81.

    Article  PubMed  CAS  Google Scholar 

  14. Roswit B, Higgins GA, Keehn RJ. Preoperative irradiation for carcinoma of the rectum and rectosigmoid colon: report of a national Veterans Administration randomized study. Cancer 1978;35:1597–1602.

    Article  Google Scholar 

  15. Stevens KR Jr, Fletcher WS, Allen CV. Anterior resection and primary anastomosis following high dose preoperative irradiation for adenocarcinoma of the recto-sigmoid. Cancer 1978;41: 2065–71.

    Article  PubMed  Google Scholar 

  16. Schrock TR, Deveney CW, Dunphy JE. Factors contributing to leakage of colonic anastomoses. Ann Surg 1973;177:513–8.

    Article  PubMed  CAS  Google Scholar 

  17. Bubrick MP, Rolfsmeyer ES, Schauer RM, et al. Effects of high-dose and low-dose preoperative irradiation and low anterior anastomoses in dogs. Dis Colon Rectum 1982;25:406–15.

    Article  PubMed  CAS  Google Scholar 

  18. Blake DP, Bubrick MP, Kochsiek GG, et al. Low anterior anastomotic dehiscence following preoperative irradiation with 6000 rads. Dis Colon Rectum 1984;27:176–81.

    PubMed  CAS  Google Scholar 

  19. Symonds CJ. Cancer of the rectum: excision after application of radium. Proc Roy Soc Med 1914;7:152.

    Google Scholar 

  20. MRC. A trial of preoperative radiotherapy in the management of operable rectal cancer. Br J Surg 1982;69:513–9.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Read at the joint meeting of the American Society of Colon and Rectal Surgeons with the Section of Colo-Proctology, Royal Society of Medicine, and the Section of Colonic and Rectal Surgery, Royal Australasian College of Surgeons, New Orleans, Louisiana, May 6 to 11, 1984.

About this article

Cite this article

Roberson, S.H., Heron, H.C., Kerman, H.D. et al. Is anterior resection of the rectosigmoid safe after preoperative radiation?. Dis Colon Rectum 28, 254–259 (1985). https://doi.org/10.1007/BF02554046

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02554046

Key words

Navigation