Abstract
Crohn's disease confined to the appendix is a rare entity, less than 50 cases having been reported. The present study reports on another 12 cases representing 6 per cent of all 194 patients operated upon for Crohn's disease in a total, unselected series. The indications for surgery were appendicitis in eight patients, appendiceal abscess in two, suspected pyosalpinx in one, and an ovarian cyst in one. The appendices were in all cases strikingly enlarged. Giant-cell granulomas, without microabscesses, were detected in all but one patient. Two patients had early septic postoperative complications. Fistulization from the cecum did not occur. The median observation time after operation was 13.8 years. Since none of the patients had further manifestations of the disease, it is concluded that patients with Crohn's disease confined to the appendix have a favorable prognosis.
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References
Present DH, Lindner AE, Janowitz HD. Granulomatous diseases of the gastrointestinal tract. Annu Rev Med 1966; 17:243–56.
Yang SS, Gibson P, McCaughey RS, Arcari FA, Bernstein J. Primary Crohn's disease of the appendix: report of 14 cases and review of the literature. Ann Surg 1979;189:334–9.
Macleod JB, Jenkins AM, Gill W. Sarcoidosis involving the vermiform appendix. JR Coll Surg Edinb 1965;10:319–23.
El-Maraghi NR, Mair NS. The histopathology of enteric infection withYersinia pseudotuberculosis. Am J Clin Pathol 1979;71:631–9.
Brahme F, Lindström C, Wenckert A. Crohn's disease in a defined population: an epidemiological study of incidence, prevalence, mortality, and secular trends in the city of Malmö, Sweden. Gastroenterology 1975;69:342–51.
Crohn BB, Ginzburg L, Oppenheimer GD. Regional ileitis: a pathological and clinical study. JAMA 1932;99:1323–9.
Meyerding EV, Bertram HF. Nonspecific granulomatous inflammation (Crohn's disease) of the appendix: a case report. Surgery 1953;34:891–4.
Cohen WN, Denbesten L. Crohn's disease with predominant involvement of the appendix. AJR 1970;110:361–3.
Brüngger HU. Morbus Crohn der Appendix. Helv Chir Acta 1978;45:827–34.
Nivatvongs S. Crohn's disease of the appendix: report of a case and review of the literature. Dis Colon Rectum 1978; 21:361–3.
Øvrum E. Right ureteral occlusion due to isolated Crohn's disease of the appendix. Scand J Urol Nephrol 1979;13:123–5.
Sellner F, Jelinek R, Dinges HP. Zum isolierten Morbus Crohn der Appendix. Wien Klin Wochenschr 1980;92:805–7.
Koslowski E, de Cort J. De ziekte van Crohn in de appendix. Tijdschr Gastroenterol 1966;9:491–3.
Wang TK, Tolnai G, Campbell JS, Sirois J, Liepa E. Crohn's disease of the appendix. Can Med Assoc J 1972;106:233–6.
Payan HM, Gilbert EF, Hafez R. Granulomatous appendicitis. Dis Colon Rectum 1981;24:432–6.
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Lindhagen, T., Ekelund, G., Leandoer, L. et al. Crohn's disease confined to the appendix. Dis Colon Rectum 25, 805–808 (1982). https://doi.org/10.1007/BF02553319
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DOI: https://doi.org/10.1007/BF02553319