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Haematological changes after renal transplantation: Differences between cyclosporin-A and azathioprine therapy

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Abstract

Haematological changes after renal transplantation in 76 patients were reviewed and the differences observed between patients treated with cyclosporin-A and prednisolone and those treated with azathioprine and prednisolone were compared. Erythrocytosis defined as haemoglobin concentration equal to or exceeding 17 g/dl occurred in 25% of patients treated with cyclosporin-A and in 11.4% of patients treated with azathioprine. Only one patient, who received cyclosporin-A, had clinical evidence of thrombosis. Eight patients treated with cyclosporin-A and five treated with azathioprine had therapeutic venesections. There was no difference in the incidence of putative risk factors for post-transplant erythrocytosis between the two groups.

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Authors and Affiliations

  1. Departments of Medicine and Surgery, University of Hong Kong, Hong Kong

    M. K. Li

  2. Government Surgical Unit, Queen Mary Hospital, Hong Kong

    K. K. Wong

Authors
  1. G. X. Fang
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  2. P. C. K. Chan
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  3. I. K. P. Cheng
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  4. M. K. Li
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  5. K. K. Wong
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  6. M. K. Chan
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Fang, G.X., Chan, P.C.K., Cheng, I.K.P. et al. Haematological changes after renal transplantation: Differences between cyclosporin-A and azathioprine therapy. International Urology and Nephrology 22, 181–187 (1990). https://doi.org/10.1007/BF02549838

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  • DOI: https://doi.org/10.1007/BF02549838

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