Skip to main content
SpringerLink
Log in

Histopathological pattern in prostatic adenocarcinomas: Is it a prognostic criterion?

  • Published:
International Urology and Nephrology Aims and scope Submit manuscript

Abstract

A total of 152 patients with prostatic carcinoma were evaluated retrospectively. Sections prepared from paraffin blocks were examined and all cases were scored according to the Gleason grading system. Prostatic adenocarcinomas were catergorized into 3 different groups of histopathological patterns: acinar, ductal and mixed. The relationships between histopathologic pattern and symptoms, clinical findings, clinical stage, Gleason scores and local or systemic progression were investigated.

It was found that patients with mixed pattern tumours presenting at later stages with more severe symptoms of prostatism had higher Gleason scores and higher progression rates compared to patients with tumors having acinar pattern.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Catalona, W. S., Scott, W. W.: Carcinoma of the Prostate. W. B. Saunders Company, Philadelphia 1986.

    Google Scholar 

  2. Kopelson, G., Harisiadis, L., Romas, N. A., Veenema, R. J., Tannenbaum, M.: Periurethral prostatic duct carcinoma.Cancer, 42, 2894 (1978).

    Article  PubMed  CAS  Google Scholar 

  3. Dube, V. E., Farnow, G. M., Greene, L. F.: Prostatic adenocarcinoma of ductal origin.Cancer, 32, 402 (1973).

    Article  PubMed  CAS  Google Scholar 

  4. Gleason, D. F., Mellinger, G. T.: Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging.J. Urol., 111, 58 (1974).

    PubMed  CAS  Google Scholar 

  5. McLaughlin, A. P., Saltzstein, S. L., McCullough, D. L., Gittes, R. F.: Prostatic carcinoma. Incidence and location of unsuspected lymphatic metastasis.J. Urol., 115, 89 (1976).

    PubMed  CAS  Google Scholar 

  6. Byar, D. P., Mostofi, F. K., and the V.A.C.U.R.G.: Carcinoma of the prostate. Prognostic evaluation of certain pathologic features in 2089 radical prostatectomies. Examined by the step section technique.Cancer, 30, 5 (1972).

    Article  PubMed  CAS  Google Scholar 

  7. Kramer, S. A., Spahr, J., Brendler, C. B., Glenn, J. F., Paulson, D. F.: Experience with Gleason's histopathologic grading in prostatic cancer.J. Urol., 124, 223 (1980).

    PubMed  CAS  Google Scholar 

  8. Rosai, J.: Male Reproductive System. The C.V. Mosby Company, Missouri 1989.

    Google Scholar 

  9. Babaian, R. J., Grunow, W. A.: Reliability of Gleason Grading System in comparing prostate biopsies with total prostatectomy specimens.Urology, 25, 564 (1985).

    Article  PubMed  CAS  Google Scholar 

  10. Lemberger, R. J., Bishop, M. C., Bates, L. P., Blundell, W., Ansell, I. D.: Carcinoma of the prostate of ductal orgin.Br. J. Urol., 56, 706 (1984).

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Urology, Hacettepe University Hospital, Ankara, Turkey

    K. Bircan, I. Başar, A. Ergen, S. Tekgül & H. A. Özen

  2. Department of Pathology, Hacettepe Univeristy Hospital, Ankara, Turkey

    G. Özbay

Authors
  1. K. Bircan
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. I. Başar
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. Ergen
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. S. Tekgül
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. G. Özbay
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. H. A. Özen
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bircan, K., Başar, I., Ergen, A. et al. Histopathological pattern in prostatic adenocarcinomas: Is it a prognostic criterion?. International Urology and Nephrology 23, 57–64 (1991). https://doi.org/10.1007/BF02549729

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02549729

Keywords

Search

Navigation