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Lipids and lipogenic enzymes in adipose tissue of castrated male goats

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Lipids

Abstract

Male goats (“Criolla Argentina” breed), castrated at 45 days of age, showed altered lipid metabolism 180 days after castration as compared to control goats. Subcutaneous, perirenal and omental adipose tissues of castrated goats showed increases in fatty acid synthetase, glucose-6-phosphate dehydrogenase and NADP-isocitrate dehydrogenase activities. Castration increased the amount of total lipids and triglycerides, but did not modify the amount of cholesterol, phospholipid and protein in the three types of adipose tissue. The incorporation of [1-14C]acetate into fatty acids of subcutaneous and perirenal adipose tissue was increased in castrated goats in relation to noncastrated goats. Our results suggest that removal of gonadal steroids increases significantly the rate of lipogenesis in adipose tissue of male goats.

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Abbreviations

FAS:

fatty acid synthetase

ICD:

NADP-isocitrate dehydrogenase

G6PD:

glucose-6-phosphate dehydrogenase

GH:

growth hormone

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Author notes

  1. María S. Giménez (Member)

    Present address: carrera del investigador cientifico, Consejo Nacional de Investigaciones cientificas y Tecnicas, Argentina

Authors and Affiliations

  1. Química Biológica Il, Area Química Biológica, Facultad de Química, Bioquímica y Farmacía, Universidad Nacional de San Luis, Chacabuco y Pedernera, 5.700, San Luis, Argentina

    María S. Giménez (Member), Ana M. Ponce de Ascheri, María E. Elorza de Orellano, Liliana Oliveros, Fanny Zirulnik de Hodara, Mirta R. Bonomi & Luis A. Giménez

Authors
  1. María S. Giménez
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  2. Ana M. Ponce de Ascheri
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  3. María E. Elorza de Orellano
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  4. Liliana Oliveros
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  5. Fanny Zirulnik de Hodara
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  6. Mirta R. Bonomi
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  7. Luis A. Giménez
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Giménez, M.S., Ponce de Ascheri, A.M., Elorza de Orellano, M.E. et al. Lipids and lipogenic enzymes in adipose tissue of castrated male goats. Lipids 24, 985–987 (1989). https://doi.org/10.1007/BF02544546

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  • DOI: https://doi.org/10.1007/BF02544546

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