Abstract
The transport of 2R,4′R, 8′R-α-tocopherol and 2S,4′R,8′R-α-tocopherol from plasma into rat red blood cell membranes occurs with essentially no chiral discrimination. The previously demonstrated (10) preference of red blood cell membranes favoring 2R,4′R,8′R-α-tocopherol over the 2S,4′R, 8′R stereoisomer is shown to be due to better retention of the former compound, i.e., to preferential retention of natural vitamin E.
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Cheng, S.C., Burton, G.W., Ingold, K.U. et al. Chiral discrimination in the exchange of α-tocopherol stereoisomers between plasma and red blood cells. Lipids 22, 469–473 (1987). https://doi.org/10.1007/BF02540361
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DOI: https://doi.org/10.1007/BF02540361