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Phospholipid composition of guinea pig lung lavage

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Lipids

Abstract

Phospholipids from guinea pig lung lavage were analyzed. The total lavage phospholipid content was 2.65+0.67 mg, per gram of lung, which accounted for 85% of the total lipids in lung wash. Phosphatidylcholine (PC) accounted for over 60% of the total phospholipids. The other phospholipids factions, in order of pedominance, were phosphatidylinositol (PI), phosphatidylserine (PS), sphingomyelin (SPH), phosphatidylethanolamine (PE), phosphatidylglycerol (PG) and lysophosphatidyl-choline (LPC). Disaturated phosphatidylcholine (DSPC) comprised 80% of the total PC, and it contained ostly palmitic acid. The DSPC content of the lung lavage fluid per square meter of alveolar surface area was 5.76±0.42 mg.

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Authors and Affiliations

  1. Department of Biochemistry, Meharry Medical College, 37208, Nashville, TN

    Arshad Q. Khan, Matthew O. Sikpi & Salil K. Das

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  1. Arshad Q. Khan
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  2. Matthew O. Sikpi
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  3. Salil K. Das
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Khan, A.Q., Sikpi, M.O. & Das, S.K. Phospholipid composition of guinea pig lung lavage. Lipids 20, 7–10 (1985). https://doi.org/10.1007/BF02534355

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  • DOI: https://doi.org/10.1007/BF02534355

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