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β-oxidation of the coenzyme A esters of vaccenic, elaidic, and petroselaidic acids by rat heart mitochondria

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Lipids

Abstract

Rates of β-oxidation of the coenzyme A esters of vaccenic, elaidic, and petroselaidic acids as well as their respectivecis isomers by rat heart mitochondria were measured and compared. At all concentrations studied, vaccenoyl-CoA was oxidized more rapidly than elaidoyl-CoA, but more slowly than oleoyl-CoA except at high substrate concentrations. Alltrans octadecenoyl-CoA esters were oxidized at a slower rate than their respectivecis or saturated isomers. Oxidation rates decreased as the double bond approached the carboxyl-end.

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Author notes

  1. Larry D. Lawson

    Present address: The Hormel Institute, University of Minnesota, 801 16th Avenue N.E., 55912, Austin, MN

Authors and Affiliations

  1. Burnsides Research Laboratory, University of Illinois, 61801, Urbana, Illinois

    Larry D. Lawson & Fred A. Kummerow

Authors
  1. Larry D. Lawson
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  2. Fred A. Kummerow
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Lawson, L.D., Kummerow, F.A. β-oxidation of the coenzyme A esters of vaccenic, elaidic, and petroselaidic acids by rat heart mitochondria. Lipids 14, 501–503 (1979). https://doi.org/10.1007/BF02533469

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  • DOI: https://doi.org/10.1007/BF02533469

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