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Composition ofO-alkyl andO-alk-1-enyl moieties in the glycerolipids of the human adrenal

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Lipids

Abstract

A comparison of human adult and fetal adrenals with respect to their levels of glyceryl ether lipids and other lipid components is reported. Fetal glands contained significantly lower levels of alk-1-enyl phosphoglycerides and of cholesterol. Neutral glyceryl ether diesters, and ethanolamine and choline phosphoglycerides were isolated from adult adrenal tissue. The composition of theO-alkyl glycerol groups in these lipid fractions was obtained by means of gas chromatography of the trimethylsilyl ethers and diacetyl derivatives;O-alk-1-enyl glycerols were analyzed as their diacetates. About one-half of the alkyl and alk-1-enyl glycerol moieties present in glyceryl ether diesters contained hydrocarbon side chains with 20, 22, or 24 carbon atoms. Long hydrocarbon chains (C19–24) were also found in theO-alkyl glycerol moieties present in the total lipids of fetal adrenals.

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Authors and Affiliations

  1. Departments of Pathology and Chemistry, University of Hong Kong, Hong Kong

    Hsiang Ju Lin, M. S. F. Lie Ken Jie, Clara Lai Hing Lee & Daniel Hong Seng Lee

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  1. Hsiang Ju Lin
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  2. M. S. F. Lie Ken Jie
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  3. Clara Lai Hing Lee
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  4. Daniel Hong Seng Lee
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Lin, H.J., Lie Ken Jie, M.S.F., Hing Lee, C.L. et al. Composition ofO-alkyl andO-alk-1-enyl moieties in the glycerolipids of the human adrenal. Lipids 12, 620–625 (1977). https://doi.org/10.1007/BF02533392

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  • DOI: https://doi.org/10.1007/BF02533392

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