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Radiopharmaceuticals

I. Synthesis of radioiodinated phenylfatty acids for studying myocardial metabolism

  • Medical Radioisotopes and Control of Radiopharmaceuticals
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Abstract

For studying the metabolism of fatty acids in the heart muscle in-vivo, ω-phenylpenta-decanoic acid (PPA) was labelled with radioiodine to the ortho and para position of the benzene ring with a radiochemical yield of 60%. The products were obtained in a relative isomer distribution of 29%ortho and 71%para radioiodinated PPA. The radiopharmaceutical quality control was performed by sequential radio high pressure liquid chromatography.

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Authors and Affiliations

  1. Institut für Med. Strahlenphysik und Strahlenbiologie des Universitätsklinikum Essen, Hufelandstr. 55, D-4300, Essen, (BRD)

    H. -J. Machulla, M. Marsmann & K. Dutschka

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  1. H. -J. Machulla
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  2. M. Marsmann
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  3. K. Dutschka
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Machulla, H.J., Marsmann, M. & Dutschka, K. Radiopharmaceuticals. J. Radioanal. Chem. 56, 253–261 (1980). https://doi.org/10.1007/BF02516958

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  • DOI: https://doi.org/10.1007/BF02516958

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