Abstract
Experiments on C57Bl/6 mice showed that antiserotonin antibodies injected intraperitoneally in a dose of 25 mg/kg or added to cell culture in a dose of 10−7 mol/ml suppress lymphocyte proliferative response to pokeweed mitogen and stimulate functional activity of macrophages.
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References
L. A. Basharova, L. A. Vetrile, V. A. Evseev,et al., Fiziol. Zh. SSSR,74, No. 10, 1367–1371 (1988).
L. A. Basharova, V. A. Evseev, L. A. Vetrile,et al., Byull. Eksp. Biol. Med.,115, No. 5, 469–471 (1993).
L. V. Devoino and R. Yu. Il'yuchenok,Monoaminergic Systems in the Regulation of Immune Reactions (Serotonin, Dopamine) [in Russian], Novosibirsk (1983).
L. V. Devoino and R. Yu. Il'yuchenok,Neurotransmittory Systems in Psychoimmunomodulation [in Russian] Novosibirsk (1993).
O. I. Mikovskaya, V. G. Fomina, L. A. Basharova, and V. A. Evseev,Byull. Eksp. Biol. Med.,124, No. 12, 663–665 (1997).
V. P. Selezneva,The Role of Macrophagal Cells in Whooping Cough Immunity. Author's Abstract of Ph.D. Thesis, Moscow (1970).
Kh. Frimel',Immunological Methods [in Russian], Moscow (1970).
M. Bonnet, G. Lespinats, and C. Burtin,Cell. Immunol. 83, 280–291 (1984).
B. Pescar and S. Spector,Science,179, 1340–1341 (1973).
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 125, No. 2, pp. 140–142, February, 1998
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Davydova, T.B., Evseev, V.A., Fomina, V.G. et al. Effect of antiserotonin antibodies on functional activity of T and B lymphocytes and peritoneal macrophages. Bull Exp Biol Med 125, 120–122 (1998). https://doi.org/10.1007/BF02496835
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DOI: https://doi.org/10.1007/BF02496835