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Effect of hyperadrenalinemia on the contents of epinephrine and norepinephrine in rat gastrointestinal tissues

  • General Pathology and Pathological Physiology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The contents of epinephrine and norepinephrine in the salivary glands, oral, esophageal, and gastric mucosa, and in the blood after parenteral injection of epinephrine measured by high-performance liquid chromatography. It is shown that 1.5 h postinjection the content of epinephrine in all studied organs and in the blood considerably surpassed the initial level, while the content of norepinephrine sharply decreased in the mucosa and increased in the blood. It is suggested that under conditions of hyperadrenalinemia, receptory binding of epinephrine far surpasses that of norepinephrine, attesting to a competition between these catecholamines for receptors on epitheliocytes which depends on their concentration in different body fluids.

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Authors and Affiliations

  1. Department of Pathological Physiology, Medical Faculty of the Moscow Medical Stomatological Institute, Moscow, USSR

    V. V. Mikhailov, M. A. Gordeeva & V. N. Matveeva

Authors
  1. V. V. Mikhailov
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  2. M. A. Gordeeva
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  3. V. N. Matveeva
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Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 125, No. 1, pp. 38–39, January, 1998 Original

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Mikhailov, V.V., Gordeeva, M.A. & Matveeva, V.N. Effect of hyperadrenalinemia on the contents of epinephrine and norepinephrine in rat gastrointestinal tissues. Bull Exp Biol Med 125, 30–31 (1998). https://doi.org/10.1007/BF02496794

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  • DOI: https://doi.org/10.1007/BF02496794

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