Abstract
The reactions ofp-chlorobenzoyl- and benzoylpyruvic acids withS-methylisothiosemicarbazide hydroiodide gave 3-methylthio-6-(p-chlorophenacyl)-2,5-dihydro-1,2,4-triazin-5-one and 6-phenacyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5,-dione, respectively. The molecular and crystal structures of the compounds synthesized were studied by X-ray diffraction analysis.
Similar content being viewed by others
References
C. Bulow,Ber., 1904,34, 2198.
V. S. Zalesov, Yu. S. Andreichikov, Yu. A. Nalimova, S. P. Tendryakova, S. M. Starkova, and N. A. Podushkina,Khim. -farm. Zh., 1978,7, 93 [Pharm. Chem. J., 1978,7 (Engl. Transl.)].
Yu. S. Andreichikov, T. N. Tokmakova, L. A. Voronova, and Yu. A. Nalimova,Zh. Org. Khim., 1976,12, 1073 [J. Org. Chem. USSR, 1976,12 (Engl. Transl.)].
R. B. Moffett,J. Med. Chem., 1966,9, 475.
S. Bodforss,Lieb. Ann., 1964,676, 136.
G. S. Predvoditeleva, T. V. Kartseva, and M. N. Shchukina,Khim. -farm. Zh., 1974,9, 7 [Pharm. Chem. J., 1974,9 (Engl. Transl.)].
V. P. Kruglenko, V. P. Gnidets, N. A. Klyuev, E. V. Legachev, M. A., Klykov, and M. V. Povstyanoi,Khim. Geterotsikl. Soedin., 1985, 1402 [Chem. Heterocycl. Compd., 1985 (Engl. Transl.)].
T. N. Yanborisov, I. A. Zhikina, O. Ya. Yanborisova, S. N. Shurov, and Yu. S. Andreichikov,Zh. Org. Khim., 1992,28, 2554 [Russ. J. Org. Chem., 1992,28 (Engl. Transl.)].
D. D. Nekrasov, S. N. Shurov, O. I. Ivanenko, and Yu. S. Andreichikov,Zh. Org. Khim., 1994,30, 126 [Russ. J. Org. Chem., 1994,30 (Engl. Transl.)].
Z. G. Aliev, L. O. Atovmyan, A. M. Mikhailova, L. M. Pisarenko, and V. I. Nikulin,Zh. Strukt. Khim., 1989,6, 164 [J. Struct. Chem., 1989,6 (Engl. Transl.)].
Yu. S. Andreichikov, D. D. Nekrasov, M. A. Rudenko, and Yu. A. Nalimova,Khim. Geterotsikl. Soedin., 1988, 1411 [Chem. Heterocycl. Compd., 1988 (Engl. Transl.)].
A. V. Milyutin, N. V. Safonova, L. F. Goleneva, Yu. S. Andreichikov, G. A. Tul'bovich, and R. R. Makhmudov,Khim. -farm. Zh., 1994,12, 37 [Pharm. Chem. J., 1994,12 (Engl. Transl.)].
Yu. S. Andreichikov, L. I. Varkentin, S. G. Pitirimova, and Ya. M. Vilenchik,Khim. Geterotsikl. Soedin., 1977 1126 [Chem. Heterocycl. Compd., 1977 (Engl. Transl.)].
Yu. S. Andreichikov, Yu. A. Nalimova, S. P. Tendryakova, and Ya. M. Vilenchik,Zh. Org. Khim., 1978,14, 160 [J. Org. Chem. USSR, 1978,14 (Engl. Transl.)].
G. M. Sheldrick, SHELX-86,Programm for Crystal Structure Determination, University of Cambridge, UK, 1986.
G. M. Sheldrick,J. Appl. Crystallogr., 1993,26, 593.
Author information
Authors and Affiliations
Additional information
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 4, pp. 704–708, April, 1998.
Rights and permissions
About this article
Cite this article
Aliev, Z.G., Atovmyan, L.O., Andreichikov, Y.S. et al. Reactions of aroylpyruvic acids withS-methylisothiosemicarbazide hydroiodide and studies of the crystal structures of the reaction products. Russ Chem Bull 47, 682–686 (1998). https://doi.org/10.1007/BF02495979
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/BF02495979