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Synthesis of ethyl 3-oxo-2-(3,4,5-trifluoro-2,6-dimethoxybenzoyl)butyrate

  • Organic Chemistry
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Russian Chemical Bulletin Aims and scope

Abstract

Ethyl acetoacetate was acylated with 3,4,5-trifluoro-2,6-dimethoxybenzoyl chloride to give, for the first time, ethyl 3-oxo-2-(3,4,5-trifluoro-2,6-dimethoxybenzoyl)butyrate and its copper chelate. The title compound was used for the synthesis of 6,7,8-trifluoro-5-hydroxy-2-methylchromone, 1-(3,4,5-trifluoro-2,6-dimethoxyphenyl)butane-1,3-dione, and its copper chelate.

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Authors and Affiliations

  1. Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 20 ul. S. Kovalevskoi, 620219, Ekaterinburg, Russian Federation

    S. P. Kisil', M. I. Kodess, Ya. V. Burgart & V. I. Saloutin

Authors
  1. S. P. Kisil'
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  2. M. I. Kodess
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  3. Ya. V. Burgart
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  4. V. I. Saloutin
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Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 6, pp. 1096–1098, June, 2000.

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Kisil', S.P., Kodess, M.I., Burgart, Y.V. et al. Synthesis of ethyl 3-oxo-2-(3,4,5-trifluoro-2,6-dimethoxybenzoyl)butyrate. Russ Chem Bull 49, 1090–1092 (2000). https://doi.org/10.1007/BF02494900

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  • DOI: https://doi.org/10.1007/BF02494900

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