Abstract
A mechanism is described which accounts for the active transport of Na+ ions through a membrane. It is assumed that at one side of the membrane the ion combines with a carrier ion, the resulting carrier compound then diffuses through the membrane and decomposes at the other side of the membrane. The free diffusion of the ions is also taken into account. The time rate of accumulation of the ion in question at the latter side of the membrane is calculated in terms of the concentrations of the ion at both sides of the membrane.
Similar content being viewed by others
Literature
Hodgkin, A. L., A. F. Huxley, and B. Katz. 1949. “Ionic Currents Underlying Activity in the Giant Axon of the Squid.”Arch. Sci. Physiol.,3, 129–50.
Steinbach, H. G. 1951.Ion Exchange and Permeability in Nerve Impulse. I. New York: Josiah Macy, Jr., Foundation.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Karreman, G. Some considerations on a carrier mechanism as a model for ion accumulation. Bulletin of Mathematical Biophysics 15, 161–165 (1953). https://doi.org/10.1007/BF02476381
Issue Date:
DOI: https://doi.org/10.1007/BF02476381