Abstract
Assuming a spherical geometry for the left ventricle, passive elastic stiffness-stress relations have been obtained on the basis of linear elasticity theory and large deformation theory. Employing pressure-volume aata taken from rat hearts of various age groups, it is shown that young rat heart muscle (1 month) is stiffer than either adult (7 months) or old rat heart muscle (17 months). Although the qualitative results are similar for both elasticity theories, the large deformation theory gave results in closer agreement with those obtained from papillary muscle studies. These results imply that stiffness of muscleper se can be assessed from left ventricular pressure-volume data.
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Mirsky, I., Janz, R.F., Kubert, B.R. et al. Passive elastic wall stiffness of the left ventricle: A comparison between linear theory and large deformation theory. Bltn Mathcal Biology 38, 239–251 (1976). https://doi.org/10.1007/BF02459557
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DOI: https://doi.org/10.1007/BF02459557