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Direct antiatherogenic effect of garlic

  • Experimental Methods for Clinical Practice
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Blood serum of patients with documented coronary atherosclerosis induces intracellular cholesterol accumulation in a primary culture of human aortic intimal cells. Serum prepared from blood collected 2–4 h after administration of a tablet containing 300 mg garlic powder (Kwai, Germany) induces a much lower cholesterol accumulation in cultured cells. A tablet with the same amount of garlic but with a prolonged effect (Allikor, Russia) lowers serum atherogenicity for 12–14 h. The direct antiatherogenic effect of garlic powder is confirmed by cell culture experiments with aqueous extracts from garlic powder.

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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121, No. 6, pp. 695–697, June, 1996

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Orekhov, A.N., Tertov, V.V., Sobenin, I.A. et al. Direct antiatherogenic effect of garlic. Bull Exp Biol Med 121, 629–631 (1996). https://doi.org/10.1007/BF02447137

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  • DOI: https://doi.org/10.1007/BF02447137

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