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Effects of amphazide (a hydrazide of phosphorylated carboxylic acids) and tetramezine (a diaziridine derivative) on central dopaminergic structures

  • Pharmacology and Toxicology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Amphazide and tetramezine, two recently synthesized compounds with antidepressant and nootropic activities, were found to have dopamine-positive activity in animals injected with apomorphine, L-Dopa, or haloperidol. Amphazide expressed this activity in most tests only when given in multiple doses, whereas tetramezine expressed it well even after a single dose.

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Authors and Affiliations

  1. State Medical University, Kazan

    A. Z. Baichurina, I. I. Semina & R. S. Garaev

Authors
  1. A. Z. Baichurina
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  2. I. I. Semina
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  3. R. S. Garaev
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121, No. 6, pp. 648–651, June, 1996

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Baichurina, A.Z., Semina, I.I. & Garaev, R.S. Effects of amphazide (a hydrazide of phosphorylated carboxylic acids) and tetramezine (a diaziridine derivative) on central dopaminergic structures. Bull Exp Biol Med 121, 584–586 (1996). https://doi.org/10.1007/BF02447124

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  • DOI: https://doi.org/10.1007/BF02447124

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