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Differences in NO generation during heat shock in genetically different populations of rats

  • Biophysics and Biochemistry
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The content of NO in the kidneys, heart, and spleen of intact August rats surpasses that of Wistar rats. After heat shock the content of NO rises: in the kidneys 15.5-fold, in the liver 3.2-fold, in the heart 10-fold, in the spleen 6.4-fold, in the intestine 2.8-fold, and in the brain 1.9-fold. Thus, August rats, which are less resistant to heat shock than Wistar rats, are characterized by a more pronounced activation of NO synthesis in response to heat shock.

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Authors and Affiliations

  1. Laboratory of Physical Chemistry of Biopolymers, Institute of Chemical Physics, Russian Academy of Sciences, Moscow

    V. D. Mikoyan, L. N. Kubrina & A. F. Vanin

  2. Laboratory of Membrane Mechanisms of Adaptation, Research Institute of General Pathology and Pathological Physiology, Russian Academy of Medical Sciences, Moscow

    E. B. Manukhina

  3. Laboratory of Genetic Mechanisms of Adaptation, Research Institute of General Pathology and Pathological Physiology, Russian Academy of Medical Sciences, Moscow

    E. V. Malysheva & I. Yu. Malyshev

Authors
  1. V. D. Mikoyan
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  2. L. N. Kubrina
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  3. E. B. Manukhina
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  4. E. V. Malysheva
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  5. I. Yu. Malyshev
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  6. A. F. Vanin
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121, No. 6, pp. 634–637, June, 1996

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Mikoyan, V.D., Kubrina, L.N., Manukhina, E.B. et al. Differences in NO generation during heat shock in genetically different populations of rats. Bull Exp Biol Med 121, 572–575 (1996). https://doi.org/10.1007/BF02447120

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  • DOI: https://doi.org/10.1007/BF02447120

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