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Effect of fibronectin on the generation of superoxide anion by neutrophils in alimentary toxicoinfections and experimental salmonella endotoxemia

  • General Pathology and Pathological Physiology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Production of O2 by neutrophils and the effect of fibronectin on it are studied in patients with alimentary toxicoinfections and in rats with salmonella endotoxemia. Fibronectin is found to affect the generation of superoxide anion by neutrophils, the nature of its effect depending on the number of neutrophils and background free radical activity. Fibronectin stimulates the suppressed and lowers the enhanced generation of O2 by neutrophils.

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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121, No. 6, pp. 628–631, June, 1996

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Poluektova, V.B., Globa, A.G., Khitrov, N.K. et al. Effect of fibronectin on the generation of superoxide anion by neutrophils in alimentary toxicoinfections and experimental salmonella endotoxemia. Bull Exp Biol Med 121, 566–568 (1996). https://doi.org/10.1007/BF02447118

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  • DOI: https://doi.org/10.1007/BF02447118

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