Skip to main content
SpringerLink
Log in

Relationship between the antiaggressive properties of buspirone and the time of day

  • Pharmacology and Toxicology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Buspirone administered in the morning or evening completely suppressed the interspecies aggressiveness of isolated rats expressed as attacks on and bites of mice; muricidal behavior (killing of mice) was blocked by the drug only if it was administered in the evening. Electrolytic destruction of serotonin-containing structures of the midbrain levels the phase dependence of the antimuricidal properties of buspirone.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. J. Bures, O. Buresova, and D. P. Houston,Paradigms for Research in Neural Mechanisms, Wiley (1988).

  2. B. N. Kogan and N. V. Nechaev,Lab. Delo, No 5, 346–348 (1979).

    Google Scholar 

  3. I. V. Komissarov, V. I. Dulenko, N. Ya. Kharin,et al., Farmakol. Toksikol., No 2, 27–30 (1989).

    Google Scholar 

  4. A. M. Konorskii,Histochemistry [in Russian], Kiev (1976).

  5. A. N. Kubynin,Zh. Vyssh. Nervn. Deyat.,38, No 1, 172–175 (1988).

    CAS  Google Scholar 

  6. G. F. Lakin,Biometry [in Russian], Moscow (1990).

  7. E. M. Nikulina,Zh. Vyssh. Nervn. Deyat.,41, No 6, 1149–1153 (1991).

    CAS  Google Scholar 

  8. V. P. Poshivalov,Experimental Psychopharmacology of Aggressive Behavior [in Russian], Leningrad (1986).

  9. Y. Akiyoshi, H. Kuranaga, and K. Tsuchiyama,Pharmacol. Biochem. Behav.,32, No 2, 491–493 (1989).

    Article  PubMed  CAS  Google Scholar 

  10. M. L. Leavitt, J. C. Maroon, E. L. Riley, and S. Yodofsky,FASEB J., No 3, 295 (1989).

    Google Scholar 

  11. V. V. Petkov and S. Yanev,Pharmacol. Res. Commun., No 8, 739–744 (1982).

    Google Scholar 

  12. W. Weiner, H. Clement, M. Rotsh,et al., J. Interdiscipl. Cycle Res.,21, No 2, 119–128 (1990).

    Google Scholar 

  13. L. O. Wilkinson, E. Abercrombie, K. Rusmussen, and B. Yacobs,Eur. J. Pharmacol., No 1, 25 (1987).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Human and Animal Physiology, State University; Department of Pharmacology, Siberian Medical University, Tomsk

    T. A. Zamoshchina, E. N. Ladyzhets & A. S. Saratikov

Authors
  1. T. A. Zamoshchina
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. E. N. Ladyzhets
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. S. Saratikov
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121, No 3, pp. 291–294, March, 1996

Rights and permissions

Reprints and permissions

About this article

Cite this article

Zamoshchina, T.A., Ladyzhets, E.N. & Saratikov, A.S. Relationship between the antiaggressive properties of buspirone and the time of day. Bull Exp Biol Med 121, 268–270 (1996). https://doi.org/10.1007/BF02446766

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02446766

Key Words

Search

Navigation