Abstract
Monoclonal antibodies ICO-60 clustered as CDw50 (anti-ICAM-3) drastically boosted the chemiluminescence of human neutrophils, depending on the dose of antibodies, initial chemiluminescence, and individual human reactivity. The contact-adhesion interactions of neutrophils treated with ICO-60 and of intact neutrophils were associated with intensification of chemiluminescence. ICO-60 sharply increased the adhesion and aggregation of human neuroblasts and suppressed these phenomena induced by phorbol ester. The expression of ICAM-3 on neuroblasts is proposed.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121, No. 4, pp. 447–449, April, 1996
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Zemskov, V.M., Volkov, Y.T., Torina, E.D. et al. Phagocyte activation with anti-ICAM-3 monoclonal antibodies. Bull Exp Biol Med 121, 407–409 (1996). https://doi.org/10.1007/BF02446742
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DOI: https://doi.org/10.1007/BF02446742