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Effect of nitric oxide and cyclic guanosine monophosphate on the desensitization of choline receptors in snail neurons

  • Pharmacology and Toxicology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Desensitization of choline receptors is studied after pharmacological effects on the intracellular level of nitric oxide and cyclic guanosine monophosphate in snail neurons. It is shown that inhibitors of NO synthase do not alter desensitization, whereas an activator of guanylate cyclase as well as intracellular injection of guanosine monophosphate boost it.

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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121, No. 4, pp. 426–429, April, 1996

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Pivovarov, A.S., Drozdova, E.I. Effect of nitric oxide and cyclic guanosine monophosphate on the desensitization of choline receptors in snail neurons. Bull Exp Biol Med 121, 388–391 (1996). https://doi.org/10.1007/BF02446736

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  • DOI: https://doi.org/10.1007/BF02446736

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