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Enhancement of liver cell proliferation by GM3 ganglioside

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Abstract

In experiments on rats subjected to partial hepatectomy and experimentally induced hepatitis it is shown that GM3 ganglioside of equine erythrocytes can enhance liver cell proliferation. The effect was also observed in experiments on a primary hepatocyte culturein vitro; moreover, enhancement of cell proliferation did not depend on the type of sialic acid residues.

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Authors and Affiliations

  1. Biolek Enterprise, Kharkov

    R. F. Menzeleev & Yu. M. Krasnopol'skyii

  2. Institute of Biology, Kharkov University, Moscow

    A. I. Bozhkov

  3. Department of Biotechnology, M. V. Lomonosov State Academy of Fine Chemicals Technology, Moscow

    E. N. Zvonkova & V. I. Shvets

Authors
  1. R. F. Menzeleev
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  2. A. I. Bozhkov
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  3. E. N. Zvonkova
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  4. Yu. M. Krasnopol'skyii
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  5. V. I. Shvets
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Corresponding author

Correspondence to R. F. Menzeleev.

Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 119, No 4, pp 427–430, April, 1995

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Menzeleev, R.F., Bozhkov, A.I., Zvonkova, E.N. et al. Enhancement of liver cell proliferation by GM3 ganglioside. Bull Exp Biol Med 119, 414–417 (1995). https://doi.org/10.1007/BF02445908

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  • DOI: https://doi.org/10.1007/BF02445908

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