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Role of the interaction between different types of serotonin and α2-adrenergic receptors in the regulation of audiogenic seizures in DBA/2 micereceptors in the regulation of audiogenic seizures in DBA/2 mice

  • Pharmacology and Toxicology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

It is shown that the serotonin receptors 5-HT1c, 5-HT3, and 5-HT4 and α2-adrenergic receptors are involved in the regulation of audiogenic seizures in DBA/2 mice, and that the effects of these serotonin receptors on the duration and magnitude of convulsive activity are the opoosite of those produced by α2-adrenergic receptors.

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Authors and Affiliations

  1. Laboratory for Biophysics of Receptors, Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino

    T. P. Semenova

  2. University of Texas Health Science Center, San Antonio, USA

    M. K. Ticku

Authors
  1. T. P. Semenova
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  2. M. K. Ticku
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 119, No 4, pp. 381–383, April, 1995

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Semenova, T.P., Ticku, M.K. Role of the interaction between different types of serotonin and α2-adrenergic receptors in the regulation of audiogenic seizures in DBA/2 micereceptors in the regulation of audiogenic seizures in DBA/2 mice. Bull Exp Biol Med 119, 368–370 (1995). https://doi.org/10.1007/BF02445895

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  • DOI: https://doi.org/10.1007/BF02445895

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