Abstract
The development of adaptation during stress is studied. At the early stages, adaptation exerts no protective effect: the activities of superoxide dismutase and catalase and the resistance and the Ca-transporting system of the myocardial sarcoplasmic reticulum to heat inactivation and high calcium concentrations decline. At the end of adaptation, superoxide dismutase and catalase activities increase, the function of the sarcoplasmic reticulum Catransporting system is improved, and the resistance of this system to high Ca concentrations increases compared with that in the control (1.4-fold) and during the early stages of adaptation (1.6-fold). The resistance to heat inactivation increased 1.5-fold compared with the control. Three days after the completion of adaptation, the activities of these enzymes and the resistance of Ca transport to heat inactivation and high Ca concentrations are lower than immediately after adaptation, but higher than in the control group and during the early adaptation period.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 123, No. 3, pp. 272–276, March, 1997
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Sazontova, T.G., Golantsova, N.E. & Arkhipenko, Y.V. Adaptation to stress enhances the resistance of the calcium pump in rat myocardial sarcoplasmic reticulum. Bull Exp Biol Med 123, 235–238 (1997). https://doi.org/10.1007/BF02445412
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DOI: https://doi.org/10.1007/BF02445412