Skip to main content
Log in

Role of prostaglandin E2 in neurohumoral regulation of the cardiovascular system

  • Biophysics and Biochemistry
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The role of prostaglandin E in neurohumoral regulation of visceral functions is studied. Prostaglandin E2 modulates cholinergic reflex reactions of the cardiovascular system and activates cardiovascular receptors related to unmyelinated fibers of the bulbar afferent system. The depressor effects of prostaglandin E2 are fully expressed only when bulbar cardiovascular innervation is preserved.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Kh. M. Markov,Kardiologiya, No. 3, 13–24 (1982).

    Google Scholar 

  2. F. Z. Meerson,Pathogenesis and Prevention of Stress-Induced and Ischemic Damage [in Russian], Moscow (1984).

  3. V. I. Savchuk and Z. A. Nechaeva,Physiology and Biochemistry of Mediatory Processes [in Russian], Moscow (1985).

  4. N. A. Sokolova, “Endogenous modulators of vegetative regulation of the heart (opioid- and adrenergic mechanisms),” Author's Synopsis of Doct. Biol. Sci. Dissertation [in Russian], Moscow (1992).

  5. V. V. Sherstnev and A. I. Gromov,Neirofiziologiya,12, No. 3, 239–245 (1980).

    CAS  Google Scholar 

  6. H. M. Coleridge and C. G. Coleridge,Acta Physiol. Pol.,29, No. 17, 55–79 (1978).

    PubMed  Google Scholar 

  7. H. M. Coleridge and C. G. Coleridge,Annu. Rev. Physiol.,42, 413–417 (1980).

    Article  PubMed  CAS  Google Scholar 

  8. P. Hedqvist, in:Autonomic Neurotransmission. The Prostaglandins, Vol. 1, New York (1973), pp. 101–131.

  9. O. Kadlez and K. Maschek, in:Prostaglandins in Experiment and Clinics [Russian translation], Moscow (1978).

  10. Y. A. Natanson,Physiol. Rev.,57, No. 2, 157 (1977).

    Google Scholar 

  11. Ph. Needleman,Fed. Proc.,35, 2376–2381 (1976).

    PubMed  CAS  Google Scholar 

  12. I. Staszewska-Barczak, S. N. Ferreira, and I. R. Vane,Cardiovasc. Res.,10, 314–317 (1976).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 123, No. 5, pp. 538–541, May, 1997

Rights and permissions

Reprints and permissions

About this article

Cite this article

Savchuk, V.I., Nechaeva, Z.A. & Runikhin, A.Y. Role of prostaglandin E2 in neurohumoral regulation of the cardiovascular system. Bull Exp Biol Med 123, 468–470 (1997). https://doi.org/10.1007/BF02445321

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02445321

Key Words

Navigation