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Production of transmitters stimulating antitumor cytostatic activity of bone marrow cells by activated lymphocytes

  • Microbiology and Immunology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Murine lymphocytes preactivated with mitogen (both T and B) produce soluble transmitters which stimulate cytostatic activity of normal mouse bone marrow cells, tested byin vitro inhibition of P815 mastocytoma and L1210 lymphoma cell growth. γ-Interferon is one of T-cell products stimulating antitumor activity of bone marrow cells. Cytostatic activity stimulated by T-cellular soluble transmitters is another characteristic of bone marrow cells isolated from nude mice.

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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 125, No. 6, pp. 660–662, June, 1998

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Seledtsov, V.I., Taraban, V.Y., Seledtsova, G.V. et al. Production of transmitters stimulating antitumor cytostatic activity of bone marrow cells by activated lymphocytes. Bull Exp Biol Med 125, 585–587 (1998). https://doi.org/10.1007/BF02445247

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  • DOI: https://doi.org/10.1007/BF02445247

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