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Shifts in cardiac indices induced by intravenous leu-enkephalin during sympathetic and parasympathetic blockade in rats

  • General Pathology and Pathological Physiology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Effects of intravenous leu-enkephalin on heart rate, stroke volume, and minute blood volume under conditions of sympathetic and parasympathetic blockade were studied in experiments on pubertal rats anesthetized with urethane. This opioid peptide inhibits sympathetic and parasympathetic control on the heart, affecting not only chronotropic but inotropic cardiac indices.

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Translated fromByulleten' Eksperimental'noi Biologii I Meditsiny, Vol. 125, No. 6, pp. 623–625, June, 1998

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Sitdikov, F.G., Makarenko, T.G. Shifts in cardiac indices induced by intravenous leu-enkephalin during sympathetic and parasympathetic blockade in rats. Bull Exp Biol Med 125, 550–552 (1998). https://doi.org/10.1007/BF02445236

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  • DOI: https://doi.org/10.1007/BF02445236

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