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Free radical oxidation and antioxidant activity in placental tissue in preterm labor

  • Biophysics and Biochemistry
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Effect of specific scavengers of reactive oxygen species on free-radical oxidation is studied in central and peripheral zones of the placenta from preterm delivering women (32–36 weeks) using the chemiluminescence method. A lower contribution of hypochlorite into free-radical processes and a reduced content of nonprotein SH-groups in the placenta are observed, superoxide dismutase, catalase, and total antioxidant activity being unchanged. It can be assumed that the reduced contribution of hypochlorite into free-radical processes is partially responsible for impaired antimicrobial barrier between mother and fetus in preterm labor.

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Authors and Affiliations

  1. Department of Obstetrics, Laboratory of Perinatal Biochemistry, D. O. Ott Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences, St. Petersburg

    V. M. Prokopenko, A. V. Arutyunyan, E. V. Frolova, T. U. Kuz'minykh & E. K. Ailamazyan

Authors
  1. V. M. Prokopenko
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  2. A. V. Arutyunyan
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  3. E. V. Frolova
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  4. T. U. Kuz'minykh
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  5. E. K. Ailamazyan
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 124, No. 12, pp. 632–634, December, 1997

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Prokopenko, V.M., Arutyunyan, A.V., Frolova, E.V. et al. Free radical oxidation and antioxidant activity in placental tissue in preterm labor. Bull Exp Biol Med 124, 1182–1184 (1997). https://doi.org/10.1007/BF02445114

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  • DOI: https://doi.org/10.1007/BF02445114

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