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Participation of humoral factors in the regulation of hemopoiesis in cytostatic myelodepression

  • General Pathology and Pathological Physiology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Production of hemopoietic factors responsible for colony-stimulating and erythropoietic activities by hemopoietic microenvironment is measured and the serum level of these activities in CBA mice treated with various cytostatics is determined. It is shown that the key role in direct stimulation of suppressed hemopoiesis is played by hemopoietic growth factors produced by adherent and nonadherent cells of hemopoietic microenvironment.

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Authors and Affiliations

  1. Institute of Pharmacology, Tomsk Research Center, Russian Academy of Medical Sciences, Tomsk, USSR

    A. M. Dygai, V. V. Zhdanov, M. Yu. Minakova & E. D. Gol'dberg

Authors
  1. A. M. Dygai
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  2. V. V. Zhdanov
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  3. M. Yu. Minakova
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  4. E. D. Gol'dberg
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 124, No. 8, pp. 161–165, August, 1997

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Dygai, A.M., Zhdanov, V.V., Minakova, M.Y. et al. Participation of humoral factors in the regulation of hemopoiesis in cytostatic myelodepression. Bull Exp Biol Med 124, 764–767 (1997). https://doi.org/10.1007/BF02445085

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  • DOI: https://doi.org/10.1007/BF02445085

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