Abstract
Injection of a synthetic analog of parathyroid hypertensive factor to WKY rats considerably increases and prolongs pressor response to adrenaline. Synthetic analog injected after adrenaline induces a short-term (3–4 min) and potent (to 250%) rise of arterial pressure. Each subsequent injection of the synthetic analog induces a less pronounced in the amplitude and duration pressor response. The α-adrenoblocker phentolamine completely abolishes the effects of the parathyroid hypertensive factor analog.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 124, No. 8, pp. 148–150, August, 1997
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Klyueva, N.Z., Ryzhov, D.B., Kulikov, S.V. et al. Specific response to adrenaline in arterial hypertension induced by exogenous calcium deficiency. Bull Exp Biol Med 124, 751–753 (1997). https://doi.org/10.1007/BF02445081
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DOI: https://doi.org/10.1007/BF02445081