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Effect of a preparation of exogenous histone administered by different routes on intraspecific aggression in male mice

  • Pharmacology and Toxicology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

A study is made of the effect of a preparation of exogenous histone from calf thymus administered intranasally and intraperitoneally on intraspecific aggression in male mice. The histone is shown to exert a short-term suppressive effect on aggression with both routes of administration which manifests itself in a reduced number of attacks. However, the effective doses with intranasal administration are considerably lower than in the case of intraperitoneal injections.

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References

  1. D. Al-Sufi, O. A. Goryukhina, G. P. Dem'yanenko, and Yu. V. Bobryshev,Vestn. Leningrad. Universiteta, Ser. 3, Vol. 3, No 17, 122 (1991).

    Google Scholar 

  2. A. A. Kamenskii, N. Yu. Sarycheva, E. Yu. Baturina, and I. P. Ashmarin,Vestn. Akad. Med. Nauk SSSR, No 10, 43 (1988).

    PubMed  Google Scholar 

  3. S. N. Novikov, in:Pheromones and Reproduction in Mammals: Physiological Aspects [in Russian], Leningrad (1988), p. 169.

  4. V. P. Poshivalov, in:Experimental Psychopharmacology of Aggressive Behavior [in Russian], Leningrad (1986), p. 175.

  5. W. M. Pardridge, D. Triguero, and J. Buciak,J. Pharmacol. Exp. Ther.,251, No 3, 821 (1989).

    PubMed  CAS  Google Scholar 

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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 120, No 9, pp. 271–272, September, 1995

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Gladysheva, O.S., Goryukhina, O.A. & Troitskaya, V.T. Effect of a preparation of exogenous histone administered by different routes on intraspecific aggression in male mice. Bull Exp Biol Med 120, 911–912 (1995). https://doi.org/10.1007/BF02445014

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  • DOI: https://doi.org/10.1007/BF02445014

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