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Morphofunctional aspects of liver regeneration in experimental correction of toxic hepatitis

  • Morphology and Pathomorphology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

It is demonstrated that cytoplasmic extract of rat pup liver stimulates cellular and intracellular regeneration of hepatocytes exposed to the toxic agent CCl4. Injection of liver cytosol stabilizes lysosomal membranes, increases the coefficient of energy efficiency of mitochondria, and activates proliferation of polyploid hepatocytes.

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References

  1. V. Ya. Brodskii,Zh. Obshch. Biol.,25, No 1, 39–50 (1984).

    Google Scholar 

  2. A. V. Govorkov, N. V. Zav'yalov, A. K. Balabanova,et al., Uspekhi Gepatol.,14, 238–250 (1988).

    Google Scholar 

  3. A. A. Zavarzin,DNA Synthesis and Kinetics of Cell Populations in Mammalian Ontogenesis [in Russian], Leningrad (1967).

  4. P. M. Kochergin and G. T. Chernenko,Recent Organotherapeutic Preparations [in Russian], Moscow (1984).

  5. A. G. Odynets, D. A. Berzinya, and A. N. Kozhukhov,Uspekhi Gepatol.,14, 250–256 (1988).

    Google Scholar 

  6. V. S. Paukov, T. A. Kazanskaya, and V. A., Frolov,Byull. Eksp. Biol. Med.,71, No 4, 122–125 (1971).

    Article  CAS  Google Scholar 

  7. A. M. Polishchuk and A. M. Urzhenko,Tsitologiya, No 9, 1143–1151 (1973).

    Google Scholar 

  8. D. S. Sarkisov and L. I. Aruin, in:Structural Basis of Adaptation and Compensation of Impaired Functions [in Russian], Moscow (1987), pp. 20–36.

  9. D. S. Sarkisov,Essays on the History of General Pathology [in Russian], Moscow (1993).

  10. V. A. Frolov,Byull. Eksp. Biol. Med.,77, No 3, 106–109 (1974).

    Google Scholar 

  11. V. A. Frolov,Pat. Fiziol., No 1, 7–13 (1988).

    Google Scholar 

  12. A. I. Sherudilo,Opt. Spektr., No 3, 543–545 (1966).

    Google Scholar 

  13. W. Mauer, H. Gerhart, and B. Schulze,Virch. Arch. Abt. B. Zellpath.,14, 361–371 (1973).

    Google Scholar 

  14. G. Rappoport and G. B. Howze,Proc. Soc. Exp. Biol. Med.,121, 1010–1016 (1966).

    Google Scholar 

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Authors and Affiliations

  1. Laboratory of Functional Morphology, Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk

    I. S. Proskuryakova

Authors
  1. I. S. Proskuryakova
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 119, No 6, pp. 656–659, June, 1995

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Proskuryakova, I.S. Morphofunctional aspects of liver regeneration in experimental correction of toxic hepatitis. Bull Exp Biol Med 119, 633–636 (1995). https://doi.org/10.1007/BF02443711

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  • DOI: https://doi.org/10.1007/BF02443711

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