Abstract
The paper describes a coupled 64-oscillator electronic simulator for modelling electrical slow-wave activity in the mammalian gastrointestinal digestive tract. The individual oscillator dynamics are based on an electronic implementation of the Hodgkin-Huxley membrane equations. The simulator is constructed to allow for versatility in terms of setting oscillator waveshapes and frequencies and intercoupling parameters. It also allows for automatic readout of the model frequency profile, which is one of the main features studied in gastrointestinal electrical activity. Results are shown illustrating frequency plateaus in a coupled chain of oscillators which have a frequency gradient when uncoupled. Frequency entrainment is also shown for the simulator connected as a tubular structure.
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Linkens, D.A., Khelfa, M. & Nicklin, G. Multioscillator simulator for gastrointestinal electrical activity modelling. Med. Biol. Eng. Comput. 21, 591–598 (1983). https://doi.org/10.1007/BF02442385
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DOI: https://doi.org/10.1007/BF02442385