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Peculiarities of cardiotropic effect of aconitine

  • Pharmacology and Toxicology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

In experiments on anesthetized cats, aconitine produced direct arrhythmogenic and cardiotoxic effects on the myocardium combined with indirect cardiotropic effects mediated via activation of extracardial nerves. Aconitine demonstrated pronounced cholinolytic properties and blocked vagal arrhythmogenic effect.

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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 129, No. 4, pp. 434–436, April, 2000

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Sheikh-Zade, Y.R., Cherednik, I.L. & Galenko-Yaroshevskii, P.A. Peculiarities of cardiotropic effect of aconitine. Bull Exp Biol Med 129, 365–366 (2000). https://doi.org/10.1007/BF02439272

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  • DOI: https://doi.org/10.1007/BF02439272

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