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Immunofluorescence in the study of amyloid nephrosis

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Abstract

The kidneys were studied by the fluorescent antibody technique in four autopsy cases of human amyloidosis and casein-induced amyloidosis in rabbits. In the cases of human amyloid nephrosis massive deposits of human gamma-globulin were identified in the glomerules, in the vascular walls, in the tubular basement membrane and in the interstitial tissue, and lipoprotein was demonstrable in the cytoplasms of the tubular epithelial cells. In experimental amyloidosis the studies revealed the presence of rabbit gamma-globulin in the glomerules and in the vascular walls.

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  1. Department of Pathology, Semmelweis Hospital, Budapest

    E. Beregi & L. Hatala

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  1. E. Beregi
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  2. L. Hatala
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Beregi, E., Hatala, L. Immunofluorescence in the study of amyloid nephrosis. Urology and Nephrology 1, 193–199 (1969). https://doi.org/10.1007/BF02426545

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  • DOI: https://doi.org/10.1007/BF02426545

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