Abstract
Crosses to determine the position of the three gene loci,h, Gc, andAlb, in the sixth linkage group of the rat used three strains, the TM strain, the ACI-alb analbuminemic congenic strain, and the abh-alb tester strain established by crossing the abh coat color tester strain and analbuminemic rats. Their genotypes were[C/C, h/h, GcB/GcB, Alb/Alb], [C/C, h i/h i,GcA/GcA, alb/alb] and[C/C, h/h, GcA/GcA, alb/alb], respectively. Determination of genotypes was performed by coat color and polyacrylamide gel electrophoresis (PAGE) of serum protein for theGc and albumin genes. The positions of the three gene loci in the VI linkage group were calculated from the recombination values from the phenotypes of progenies. According to this data, the three gene loci were inh-Gc-Alb tandem and the distances were 15.5±1.0% inh-Gc, 15.8±1.0% inh-Alb, and 0.32±0.16% inGc-Alb. These data confirmed the relationship among theGc, Alb, andApf genes in the rat as well as in humans.
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Shumiya, S., Nagase, S. Mapping of the hooded, Gc protein, and albumin gene loci in linkage group VI of the laboratory rat. Biochem Genet 26, 585–593 (1988). https://doi.org/10.1007/BF02399603
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DOI: https://doi.org/10.1007/BF02399603