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Limitations in the use of indium-111-oxine-labeled leucocytes for the diagnosis of occult infection in children

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Abstract

Fifteen children underwent scintigraphy withindium 111 (111In)-labeled white blood cells (WBC) for the detection of a local suppuration. The procedure generally contributed to a correct diagnosis. False negative results were observed in 5 children, but in two of them positive foci were also present. The missed lesions were 2 liver abscesses, 1 lung abscess, foci of osteomyelitis and 1 pericarditis. Two cases of chronic granulomatous disease are presented in which increased leucocyte accumulation was not observed in proven instances of infection.

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Authors and Affiliations

  1. Departments of Paediatrics, Radioisotopes and Radiology, Saint-Pierre Hospital, Free Universities (ULB, VUB) of Brussels, Belgium

    M. Haentjens, A. Piepsz & N. Perlmutter-Cremer

  2. Medizinische Universitätsklinik, Cologne, FRG

    E. Schell-Frederick

  3. Department of Radiotherapy, Radioisotope Laboratory, Institut J. Bordet, ULB, Brussels, Belgium

    J. Frühling

Authors
  1. M. Haentjens
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  2. A. Piepsz
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  3. E. Schell-Frederick
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  4. N. Perlmutter-Cremer
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  5. J. Frühling
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Haentjens, M., Piepsz, A., Schell-Frederick, E. et al. Limitations in the use of indium-111-oxine-labeled leucocytes for the diagnosis of occult infection in children. Pediatr Radiol 17, 139–142 (1987). https://doi.org/10.1007/BF02388092

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  • DOI: https://doi.org/10.1007/BF02388092

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