Skip to main content
SpringerLink
Log in

Distribution of aluminum species in normal urine as determined by chemical neutron activation analysis

  • Applications of Radioanalytical Methods to Biological and Clinical Systems
  • Published:
Journal of Radioanalytical and Nuclear Chemistry Aims and scope Submit manuscript

Abstract

A procedure developed for separating and quantifying non protein and protein fractions of aluminum species in urine was applied to four consecutive 24 hr collections of five healthy subjects. The total Al content of urine was determined by a chemical neutron activation analysis technique reported elsewhere. Results from the analysis of all subjects indicate that the majority of aluminum is bound to protein (>88%) with minor fractions as citrate complexes. These data are comparable with other speciation experiments with blood plasma indicating 90% of the aluminum was bound to plasma proteins.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. J. L. Greger, Ann. Rev. Nutr., 13 (1993) 43.

    CAS  Google Scholar 

  2. A. C. Alfrey, Contrib. Nephrol., 109 (1993) 110.

    Google Scholar 

  3. D. R. Crapper, S. S. Krishan, A. J. Dalton, Science, 180 (1973) 511.

    CAS  Google Scholar 

  4. R. M. Garruto, P. Brown, Lancet, 343 (1994), 989.

    Article  CAS  Google Scholar 

  5. C. R. Harrington, C. M. Wischik, F. K. Mcarthur, G. A. Taylor, J. A. Edwardson, J. M. Candy, Lancet, 343 (1994) 993.

    Article  CAS  Google Scholar 

  6. P. F. Good, D. P. Perl, Nature, 362 (1993) 418.

    Article  CAS  Google Scholar 

  7. J. P. Landsberg, B. Mcdonald, F. Watt, Nature, 36 (1992) 65.

    Google Scholar 

  8. W. D. Ehmann, W. R. Markesberg, Brain Life Chem. Reports, 11 (1994) 11.

    CAS  Google Scholar 

  9. G. F. Vonlandeghem, P. C. D'Haese, L. V. Lamberts, M. T. Debroe, Anal. Chem., 66 (1994) 216.

    Google Scholar 

  10. W. Harris, Clin. Chem. 38 (1992) 1809.

    CAS  Google Scholar 

  11. L. Öhman, R. B. Martin, Clin. Chem. 40 (1994) 598.

    Google Scholar 

  12. F. Khalil-Manesh, C. Agness, H. C. Gonick, Nephron, 52 (1989) 329.

    CAS  Google Scholar 

  13. F. Khalil-Manesh, C. Agness, H. C. Gonick, Nephron, 52 (1989) 329.

    CAS  Google Scholar 

  14. A. J. Blotcky, J. P. Claassen, F. Roman, E. P. Rack, Anal. Chem., 64 (1992) 2910.

    Article  CAS  Google Scholar 

  15. A. J. Blotcky, D. Hobson, J. D. Leffler, E. P. Rack, Anal. Chem., 48 (1976) 1084.

    Article  CAS  Google Scholar 

  16. R. R. Recker, A. J. Blotcky, J. A. Leffler, E. P. Rack, J. Lab. Clin. Med., 90 (1977) 810.

    CAS  Google Scholar 

  17. D. M. Shoop, J. P. Claassen, A. J. Blotcky, E. P. Rack, Radiochim. Acta., (in press).

  18. L. A. Currie, Anal. Chem., 40 (1968) 586.

    Article  CAS  Google Scholar 

  19. R. B. Martin, Clin. Chem., 32 (1986) 1797.

    CAS  Google Scholar 

  20. R. A. Yokel, J. Toxical, Environ. Health, 41 (1994) 131.

    CAS  Google Scholar 

  21. N. V. Hue, G. R. Craddock, F. Adams, Soil Sci. Soc. Am. J., 50 (1986) 28.

    CAS  Google Scholar 

  22. K. Diem, C. Letner, Scientific Tables, 7th ed, Ciba-Geigy, New York, 1972, p. 661.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Veterans Affairs Medical Center, Research Service, 151C, 68105, Omaha, NE, USA

    D. M. Shoop, A. J. Blotcky & E. P. Rack

  2. Department of Chemistry, University of Nebraska, 68588, Lincoln, NE, USA

    E. P. Rack

Authors
  1. D. M. Shoop
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. J. Blotcky
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. E. P. Rack
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Shoop, D.M., Blotcky, A.J. & Rack, E.P. Distribution of aluminum species in normal urine as determined by chemical neutron activation analysis. J Radioanal Nucl Chem 236, 103–106 (1998). https://doi.org/10.1007/BF02386325

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02386325

Keywords

Search

Navigation