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Theileriosis: The exposure of immunised cattle in aTheileria lawrencei enzootic area

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Summary

Three groups of steers were exposed to field challenge in aT. lawrencei-enzootic area of Kenya. Four out of five ECF-susceptible steers and four out of five steers immunised againstT. parva (Muguga) died of theileriosis, the surviving animals experiencing severe reactions. On the other hand, all five steers immunised againstT. parva (Muguga) and a strain of theileria probably homologous with the one present in the area of exposure, survived and only experienced mild reactions.

These results indicated that immunisation of cattle withT. parva (Muguga) may not necessarily protect them against field challenge with certainT. lawrencei-type strains, but that immunisation with an apparently homologous strain of theileria may well do so.

Résumé

Trois groupes de bouvillons ont été soumis à l'épreuve sur le terrain dans une région du Kenya où sévit une enzootie àT. lawrencei. Quatre sur cinq bouvillons neufs et quatre sur cinq bouvillons immunisés contreT. parva (Muguga) sont morts, les survivants éprouvant des réactions graves. D'autre part, cinq bouvillons immunisés contreT. parva (Muguga) et une souche deTheileria probablement identique à celle présente dans la région d'exposition, ont survécu et n'ont présenté que de faibles réactions.

Ces résultats montrent que l'immunisation de bovins avecT. parva (Muguga) peut ne pas les protéger nécessairement de l'épreuve sur le terrain avec certaines souches de typeT. lawrencei, mais que l'immunisation avec une souche deTheileria apparemment identique àT. lawrencei peut le faire.

Sumario

Tres groupos de novillos fueron expuestos al desafio de campo en un area de Kenya enzootica aT. lawrencei. Cuatro de cinco novillos susceptibles a la Fiebre de la Costa del Este y cuatro de cinco novillos inmunizados contraT. parva (Muguga) murieron de Theileriosis; los animales sobrevivientes experimentaron reacciones severas. De otra manera, todos los cinco novillos inmunizados contraTheileria parva (Muguga) y una cepa de theileria probablemente homologa con la presente en el area de exposición, sobrevivieron y solo experimentaron reacciones ligeras.

Estos resultados indicaron de que la inmunización del ganado conT. parva (Muguga) puede no necesariamente proteger contra el desafio de campo con ciertas capas ó tipos deT. lawrencei, pero que la inmunizacion con una cepa de theileria aparentemente homóloga puede proteger.

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References

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Authors and Affiliations

  1. Immtunological Research on Tick-borne Cattle Diseases and Tick Control Project, East African Veterinary Research Organization, Muguga, P.O. Box 32, Kikuyu, Kenya

    M. P. Cunningham, C. G. D. Brown, M. J. Burridge, A. D. Irvin, I. M. Kirimi, R. E. Purnell, D. E. Radley & G. G. Wagner

Authors
  1. M. P. Cunningham
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  2. C. G. D. Brown
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  3. M. J. Burridge
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  4. A. D. Irvin
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  5. I. M. Kirimi
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  6. R. E. Purnell
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  7. D. E. Radley
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  8. G. G. Wagner
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Additional information

On O.D.A. secondment from the A.R.C. Institute for Research in Animal Diseases, Compton, nr. Newbury, Berks., U.K. (Research Project R 2396).

Supported by a grant from Pfizer Corporation, New York.

On U.S.D.A. secondment from Plum Island Animal Disease Laboratory, Box 848, Greenport, Long Island, N.Y. 11944, U.S.A.

Project supported by the United Nations Development Programme, with the Food and Agriculture Organization of the United Nations as the Executing Agency, in co-operation with the East African Community. The Project is also supported by the Overseas Development Administration of the United Kingdom (Research Projects 2396 and 2494), the United States Department of Agriculture, the Rockefeller Foundation, the International Atomic Energy Agency and the Pfizer Corporation.

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Cunningham, M.P., Brown, C.G.D., Burridge, M.J. et al. Theileriosis: The exposure of immunised cattle in aTheileria lawrencei enzootic area. Trop Anim Health Prod 6, 39–43 (1974). https://doi.org/10.1007/BF02380747

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  • DOI: https://doi.org/10.1007/BF02380747

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