Summary
Experiments were carried out on the effects of some phenoxyacilic acids, used as herbicides, on the glutamic-dehydrogenase (GLDH) activity.
2,4-D,2,4,5-T, MCPA and Dichlorprop inhibited GLDH activity in a competitive way.
Phenoxyacilic acids were ranked in the following order of affinity for the enzyme on the basis of the values of the inhibition constants: 2,4,5-T>2,4-D>MCPA>Dichlorprop; on the basis of chemical structure, it was established that the carboxyl dissociation degree is instrumental in linking the herbicide with the active site of the enzyme.
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Polemio, M., Genchi, G., Palmieri, F. et al. Glutamic-dehydrogenase activity inhibition by phenoxyacilic acids. Plant Soil 63, 369–375 (1981). https://doi.org/10.1007/BF02370037
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DOI: https://doi.org/10.1007/BF02370037