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The effect ofin vitro fluoride ion treatment on the ultrasonic properties of cortical bone

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Abstract

The mechanical properties of composites are influenced, in part, by the volume fraction, orientation, constituent mechanical properties, and interfacial bonding. Cortical bone tissue represents a short-fibered biological composite where the hydroxyapatite phase is embedded in an organic matrix composed of type I collagen and other noncollagenous proteins. Destructive mechanical testing has revealed that fluoride ion treatment significantly lowers theZ-axis tensile and compressive properties of cortical bone through a constituent interfacial debonding mechanism. The present ultrasonic data indicates that fluoride ion treatment significantly alters the longitudinal velocity in theZ-axis as well as the circumferential and radial axes of cortical bone. This suggests that the distribution of constituents and interfacial bonding amongst them may contribute to the anisotropic nature of bone tissue.

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Author notes

  1. W. R. Walsh Ph.D.

    Present address: Centre for Biomedical Engineering, University of New South Wales, P.O. Box 1, 2033, Kensington, New South Wales, Australia

Authors and Affiliations

  1. Biomechanics Laboratory, Department of Orthopedics, Brown University School of Medicine, Rhode Island Hospital, Providence, RI

    W. R. Walsh Ph.D., D. P. Labrador & H. D. Kim

  2. Division of Engineering, Brown University, Providence, RI

    W. R. Walsh Ph.D.

  3. University of Medicine and Dentistry of New Jersey-SOM Biomechanics & Rutgers University Biomedical Engineering, Piscataway, NJ

    N. Guzelsu

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  1. W. R. Walsh Ph.D.
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  3. H. D. Kim
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  4. N. Guzelsu
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Walsh, W.R., Labrador, D.P., Kim, H.D. et al. The effect ofin vitro fluoride ion treatment on the ultrasonic properties of cortical bone. Ann Biomed Eng 22, 404–415 (1994). https://doi.org/10.1007/BF02368247

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  • DOI: https://doi.org/10.1007/BF02368247

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