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Small nuclear RNAs synthesis in PHA-stimulated and nonstimulated human peripheral blood lymphocytes

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Summary

Five fractions of small nuclear RNAs (snRNAs) were identified in nuclei of human peripheral blood lymphocytes. They have been designated as: H, G', D, C and A (nomenclature according to weinberg) in order of decreasing electrophoretic mobility. Their synthesis was observed from the first day of treatment with mitogen and was continued with different intensity during four days of culture. In nonstimuated lymphocytes exclusively A and G' fractions were detected but no (14C)-uridine incorporation was observed.

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Authors and Affiliations

  1. Institute of Human Genetics, Polish Academy of Sciences, Swiecickiego 6, 60-781, Poznań, Poland

    Jadwiga Jaruzelska, Wlodzimierz M. Stolzmann, Krzysztof Wiktorowicz & Ryszard Slomski

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  1. Jadwiga Jaruzelska
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  2. Wlodzimierz M. Stolzmann
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  3. Krzysztof Wiktorowicz
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  4. Ryszard Slomski
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Jaruzelska, J., Stolzmann, W.M., Wiktorowicz, K. et al. Small nuclear RNAs synthesis in PHA-stimulated and nonstimulated human peripheral blood lymphocytes. Mol Cell Biochem 35, 183–189 (1981). https://doi.org/10.1007/BF02357088

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  • DOI: https://doi.org/10.1007/BF02357088

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