Summary
Glycozoline and girinimbine isomers (IV andVII) were synthesized and their activity against 2 bacterial strains, viz.E. coli andS. aureus, and 2 fungal strains, viz.C. albicans andA. niger were studied. The hydroxy synthons (III) were also tested.
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Literatur
T.A. Pugsley and W. Lippmann, Experientia33, 568 (1975).
A.A. Asselin, L.G. Humber, T.A. Dobson, J. Komlossy and R.R. Martel, J. med. Chem.19, 787 (1976).
A. Shoeb, F. Anwar, R.S. Kapil, S.P. Popli, P. Dua and B.N. Dhawan, J. med. Chem.16, 425 (1973).
V.I. Shvedov, L.B. Altukhova and A.N. Grinev, Khim.-farm. Zh.3, 28 (1969); Chem. Abstr.72, 12476j (1970).
A. Mooradian, J. med. Chem.20, 487 (1977).
A. Mooradian, A.G. Hlavac, P.E. Dupont, M.R. Bell and A.A. Abousi, J. med. Chem.18, 640 (1975).
E.J. Alexander and A. Mooradian, U.S. Pat. 4,001,270 (1976); Chem. Abstr.87, 39275q (1977).
W.L. Albrecht and R.W. Fleming, U.S. Pat. 3,932,424 (1976); Chem. Abstr.84, 150498s (1976).
H. Biere, H. Ahrens, C. Rufer, E. Schroeder and H. Koch, Ger. Pat. 2,337,154 (1975); Chem. Abtr.82, 156068j (1975).
D.N. Chowdhury, S.K. Basak and B.P. Das, Curr. Sci. India47, 490 (1978).
D.P. Chakraborty, K.C. Das, B.P. Das and B.K. Chowdhury, Trans. Bose Res. Inst.38, 1 (1975).
K.C. Das, D.P. Chakraborty and P.K. Bose, Experientia21, 340 (1965).
G.D. Shah and B.P.J. Patel, Indian J. Chem.18B, 451 (1979).
F.M. Dean, in: The Total Synthesis of Natural Products, vol. 1, p. 467 and p. 534. Ed. J. Ap Simon. Wieley Interscience, New York 1973.
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The authors are thankful to Dr B.N. Apte, Association of Microbiologists of India, Bombay Unit, for providing some of the organisms, to Prof. A.K. De, Indian Institute of Technology, for financial assistance, to Prof. G. D. Shah, Department of Chemistry, Indian Institute of Technology for guidance, encouragement and helpful discussions.
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Randelia, B.E., Patel, B.P.J. Antimicrobial activity of carbazole derivatives. Experientia 38, 529–531 (1982). https://doi.org/10.1007/BF02327031
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DOI: https://doi.org/10.1007/BF02327031