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Synthesis of 6-methyl-5-phenylcarbamoyl-3,4-dihydropyridinespiro-4-cyclohexane-2(1H)-thione and its derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

3-Cyano-6-methyl-5-phenylcarbamoyl-3,4-dihydropyridinespiro-4-cyclohexane-2(1H)-thione was obtained by the condensation of acetoacetic acid anilide with cyclohexylidenecyanothioacetamide. Substituted 2-alkylthio-1,4-dihydropyridines and 3-amino-2-(4-chlorobenzoyl)-6-methyl-5-phenylcarbamoyl-4,7-dihydrothieno[2,3-b]pyridinespiro-4-cyclohexane were synthesized from it.

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References

  1. V. D. Dyachenko, S. G. Krivokolysko, V. N. Nesterov, Yu. T. Struchkov, and V. P. Litvinov, Izv. Akad. Nauk, Ser. Khim., No. 10, 2535 (1996).

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Authors
  1. V. D. Dyachenko
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  2. S. G. Krivokolysko
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  3. V. P. Litvinov
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Additional information

T. G. Shevchenko Lugansk State Pedagogical Institute, Lugansk 348011, Ukraine N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, Moscow 117913. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1533–1535, November, 1997.

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Dyachenko, V.D., Krivokolysko, S.G. & Litvinov, V.P. Synthesis of 6-methyl-5-phenylcarbamoyl-3,4-dihydropyridinespiro-4-cyclohexane-2(1H)-thione and its derivatives. Chem Heterocycl Compd 33, 1325–1327 (1997). https://doi.org/10.1007/BF02320335

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  • DOI: https://doi.org/10.1007/BF02320335

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