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Synthesis of Ethyl 5-(Arylcarbamoyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylates

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Abstract

A one-step procedure has been developed for the synthesis of previously unknown ethyl 5-(arylcarbamoyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylates by reaction of ethyl 2-cyano-3-ethoxyprop-2-enoate with acetoacetanilides in the presence of a catalytic amount of piperidine in ethanol at room temperature.

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Authors and Affiliations

  1. Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia, Yerevan, Armenia

    S. S. Hayotsyan, A. A. Sargsyan, S. G. Konkova, A. Kh. Khachatryan, A. E. Badasyan, K. A. Avagyan, H. A. Panosyan, A. G. Ayvazyan & M. S. Sargsyan

  2. State Academy of Crisis Management, Ministry of Emergency Situations of Armenia, Yerevan, Armenia

    A. Kh. Khachatryan

Authors
  1. S. S. Hayotsyan
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  2. A. A. Sargsyan
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  3. S. G. Konkova
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  4. A. Kh. Khachatryan
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  5. A. E. Badasyan
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  6. K. A. Avagyan
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  7. H. A. Panosyan
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  8. A. G. Ayvazyan
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  9. M. S. Sargsyan
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Corresponding author

Correspondence to S. S. Hayotsyan.

Additional information

Russian Text © The Author(s), 2019, published in Zhurnal Organicheskoi Khimii, 2019, Vol. 55, No. 4, pp. 561–565.

Conflict of Interests

The authors declare the absence of conflict of interests.

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Hayotsyan, S.S., Sargsyan, A.A., Konkova, S.G. et al. Synthesis of Ethyl 5-(Arylcarbamoyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylates. Russ J Org Chem 55, 469–472 (2019). https://doi.org/10.1134/S1070428019040080

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  • DOI: https://doi.org/10.1134/S1070428019040080

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