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Headspace gas chromatographic determination of ethylene oxide in air

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Summary

A simple and accurate headspace-GC method is described to determine the amount of ethylene oxide which has been collected from air using adsorption tubes containing activated charcoal and a relatively safe desorbing agent (N,N-dimethyl acetamide). The detection limit is 40μg/m3.

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References

  1. European Chemical Industry Ecology & Toxicology Centre (ECETOC) “Ethylene Oxide Toxicology and its Revelance to Man” (an updating of ECETOC technical report No 5), technical report No 11, 26 March 1984.

  2. IARC Monographs on the evaluation of the carcinogenic risk of chemicals to man. Publications of the International Agency for Research and Cancer, Lyon, Vol. 11, (1979), p. 157.

  3. NIOSH “Ethylene oxide” No S286. Documentation of the NIOSH Validation Test, U.S. Department of Health, Education and Welfare, Cincinnati, Ohio (1977).

  4. L. Gramiccioni, M. R. Milana, S. Di Marzio, Microchemical J.32, 89 (1985).

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  5. NIOSH Recommendations for Occupational Safety and Health Standards, Morbidity and Mortality Weekly report, vol. 34, No 18 Supplement, 1 October 1985.

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Binetti, R., Di Marzio, S., Di Prospero, P. et al. Headspace gas chromatographic determination of ethylene oxide in air. Chromatographia 21, 701–704 (1986). https://doi.org/10.1007/BF02313683

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  • DOI: https://doi.org/10.1007/BF02313683

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