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Chemistry of Heterocyclic Compounds

, Volume 33, Issue 12, pp 1430–1437 | Cite as

Synthesis of 4-alkyl-6-amino-3,5-dicyano-2(1H)-pyridinethiones

  • V. D. Dyachenko
  • S. G. Krivokolysko
  • V. N. Nesterov
  • V. P. Litvinov
Article

Abstract

Condensation of aliphatic aldehydes with cyanothioacetamide has given 4-alkyl-6-amino-3,5-dicyano-2(1H)-pyridinethiones, which have also been synthesized by recyclization of 4-alkyl-2,6-diamino-4H-thiopyrans. Substituted 2-alkylthiopyridines and thieno[2,3-b]pyridines have been prepared from the pyridinethiones. 2,6-Diamino-4-isopropyl-3,5-dicyano-4H-thiopyran and 6-amino-4-isobutyl-2-methylthio-3,5-dicyanopyridine have been studied by x-ray crystallography.

Keywords

Organic Chemistry Aldehyde Pyridine Aliphatic Aldehyde Cyanothioacetamide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1998

Authors and Affiliations

  • V. D. Dyachenko
  • S. G. Krivokolysko
  • V. N. Nesterov
  • V. P. Litvinov

There are no affiliations available

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