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Synthesis of 7-methyl-6-(nitroimidazolyl)thiopurines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

We have studied the reactions of 7-methyl-6-thiopurine with 5(4)-halo-4(5)-nitroimidazoles and 6-chloro-7-methylpurine with sodium and ammonium salts of 5-mercapto-4-nitroimidazoles. We have obtained a series of 7-methyl-6-(nitroimidazolyl)thiopurines not previously described in the literature.

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Authors and Affiliations

  1. Drug Chemistry Center, All-Russian Pharmaceutical Chemistry Scientific Research Institute, 119815, Moscow

    P. M. Kochergin, V. S. Korsunskii & V. S. Shlikhunova

  2. Zaporozhe State Medical University, 330074, Zaporozhe, Ukraine

    E. V. Aleksandrova

Authors
  1. P. M. Kochergin
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  2. E. V. Aleksandrova
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  3. V. S. Korsunskii
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  4. V. S. Shlikhunova
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 217–220, February, 2000.

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Kochergin, P.M., Aleksandrova, E.V., Korsunskii, V.S. et al. Synthesis of 7-methyl-6-(nitroimidazolyl)thiopurines. Chem Heterocycl Compd 36, 178–181 (2000). https://doi.org/10.1007/BF02283548

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  • DOI: https://doi.org/10.1007/BF02283548

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